Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent

Guigen Li, Dinesh Patel, Victor J Hruby

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

Original languageEnglish (US)
Pages (from-to)3057-3059
Number of pages3
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number21
StatePublished - 1994

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Isomers
Amino Acids

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

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title = "Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent",
abstract = "Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.",
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AU - Hruby, Victor J

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AB - Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

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JO - Journal of the Chemical Society, Perkin Transactions 1

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