Exploration for large-scale stereoselective synthesis of unusual amino acids by using 4-phenyloxazolidin-2-one as a new chiral resolution reagent

Guigen Li, Dinesh Patel, Victor J. Hruby

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Abstract

Individual isomers of β-branched α-amino acids have been stereoselective and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.

Original languageEnglish (US)
Pages (from-to)3057-3059
Number of pages3
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number21
StatePublished - Dec 1 1994

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ASJC Scopus subject areas

  • Chemistry(all)

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