Expression of atrial natriuretic factor (ANF) during Xenopus cardiac development

E. M. Small, Paul A Krieg

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We have isolated the Xenopus orthologue of the atrial natriuretic factor (ANF) gene. Characterization of embryonic expression indicates that the ANF gene is initially expressed throughout the developing myocardium at the late heart tube stage (about stage 32). This is in contrast to all previously characterized Xenopus cardiac differentiation markers that are first expressed in the cardiogenic plate at approximately stage 27. ANF expression becomes restricted exclusively to the atrium at about stage 47, long after the commencement of beating and the original formation of the atrial and ventricular compartments, but shortly after septation of the single atrium into two distinct atria.

Original languageEnglish (US)
Pages (from-to)638-640
Number of pages3
JournalDevelopment Genes and Evolution
Volume210
Issue number12
DOIs
StatePublished - 2000

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atrial natriuretic peptide
Xenopus
Atrial Natriuretic Factor
gene
Differentiation Antigens
myocardium
Genes
Myocardium
genes
heart
marker

Keywords

  • Atrial natriuretic factor
  • Heart
  • Septation
  • Xenopus laevis

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology
  • Genetics
  • Ecology, Evolution, Behavior and Systematics

Cite this

Expression of atrial natriuretic factor (ANF) during Xenopus cardiac development. / Small, E. M.; Krieg, Paul A.

In: Development Genes and Evolution, Vol. 210, No. 12, 2000, p. 638-640.

Research output: Contribution to journalArticle

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