Abstract
Whole mount in situ hybridization studies were performed to investigate the expression pattern of the homeobox gene Hex (also known as Prh) during early stages of chick embryogenesis. At the time of laying, cHex transcripts are detected in Koller's sickle and the forming hypoblast. During gastrulation (HH stage 4), chex is expressed in anteriorly-displaced hypoblast cells. At stage 6, cHex transcripts are observed within endoderm in an anterior arc that overlaps the cardiogenic region. Later chex expression is observed within pharyngeal endoderm immediately adjacent to the forming myocardium, in the endocardium and in the liver and thyroid gland primordia. cHex transcripts are also detected within blood islands beginning at stage 4, and in extraembryonic and intraembryonic vascular endothelial cells as vessels form.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 107-109 |
| Number of pages | 3 |
| Journal | Mechanisms of Development |
| Volume | 80 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1999 |
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Keywords
- Angiogenesis
- Blood islands
- Chicken
- Endocardium
- Hex
- Homeobox
- Hypoblast
- In situ hybridization
- Koller's sickle
- Liver
- Mesoderm
- Myocardium
- Pharyngeal endoderm
- Prh
- Thyroid
- Vascular endothelium
ASJC Scopus subject areas
- Developmental Biology
- Developmental Neuroscience
Cite this
Expression of the homeobox gene Hex during early stages of chick embryo development. / Yatskievych, Tatiana A.; Pascoe, Sharon; Antin, Parker B.
In: Mechanisms of Development, Vol. 80, No. 1, 01.1999, p. 107-109.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Expression of the homeobox gene Hex during early stages of chick embryo development
AU - Yatskievych, Tatiana A.
AU - Pascoe, Sharon
AU - Antin, Parker B
PY - 1999/1
Y1 - 1999/1
N2 - Whole mount in situ hybridization studies were performed to investigate the expression pattern of the homeobox gene Hex (also known as Prh) during early stages of chick embryogenesis. At the time of laying, cHex transcripts are detected in Koller's sickle and the forming hypoblast. During gastrulation (HH stage 4), chex is expressed in anteriorly-displaced hypoblast cells. At stage 6, cHex transcripts are observed within endoderm in an anterior arc that overlaps the cardiogenic region. Later chex expression is observed within pharyngeal endoderm immediately adjacent to the forming myocardium, in the endocardium and in the liver and thyroid gland primordia. cHex transcripts are also detected within blood islands beginning at stage 4, and in extraembryonic and intraembryonic vascular endothelial cells as vessels form.
AB - Whole mount in situ hybridization studies were performed to investigate the expression pattern of the homeobox gene Hex (also known as Prh) during early stages of chick embryogenesis. At the time of laying, cHex transcripts are detected in Koller's sickle and the forming hypoblast. During gastrulation (HH stage 4), chex is expressed in anteriorly-displaced hypoblast cells. At stage 6, cHex transcripts are observed within endoderm in an anterior arc that overlaps the cardiogenic region. Later chex expression is observed within pharyngeal endoderm immediately adjacent to the forming myocardium, in the endocardium and in the liver and thyroid gland primordia. cHex transcripts are also detected within blood islands beginning at stage 4, and in extraembryonic and intraembryonic vascular endothelial cells as vessels form.
KW - Angiogenesis
KW - Blood islands
KW - Chicken
KW - Endocardium
KW - Hex
KW - Homeobox
KW - Hypoblast
KW - In situ hybridization
KW - Koller's sickle
KW - Liver
KW - Mesoderm
KW - Myocardium
KW - Pharyngeal endoderm
KW - Prh
KW - Thyroid
KW - Vascular endothelium
UR - http://www.scopus.com/inward/record.url?scp=0032586645&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032586645&partnerID=8YFLogxK
U2 - 10.1016/S0925-4773(98)00204-4
DO - 10.1016/S0925-4773(98)00204-4
M3 - Article
C2 - 10096068
AN - SCOPUS:0032586645
VL - 80
SP - 107
EP - 109
JO - Mechanisms of Development
JF - Mechanisms of Development
SN - 0925-4773
IS - 1
ER -