Extended function of the corpus luteum and earlier development of the second follicular wave in heifers treated with bovine somatotropin

M. C. Lucy, T. L. Curran, Robert J Collier, W. J. Cole

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Effects of recombinant bovine somatotropin (bST) on growth of the corpus luteum (CL) and development of ovarian follicles were tested. Starting at estrus (Day=0), the following treatments were administered: control (saline injected Days 0 to 19, n=5); bST[0-9] (25 mg bST injected Days 0 to 9, saline injected Days 10 to 19, n=5); bST[10-19] (saline injected Days 0 to 9, 25 mg bST injected Days 10 to 19, n=5); and bST[0-19] (25 mg bST injected Days 0 to 19, n=6). Blood was collected daily for progesterone analysis, and ultrasound examinations were performed daily for measurement of follicles and CL. Compared with the heifers treated with saline, those treated with bST had larger CL and more progesterone during the early (≤ Day 10) and late (Days 15 to 21) phases of the estrous cycle. At mid-cycle (Days 10 to 15), luteal tissue area and progesterone levels were similar for bST- and saline-treated heifers. Ovarian follicular growth was similar for bST- and saline-treated heifers during the first follicular wave. However, during recruitment for the second follicular wave (Days 10 to 14), second largest follicles emerged sooner (P<0.001), the number of Class-3 (≥10 mm) follicles was greater (P<0.01) and largest follicles were smaller (P<0.001) in bST than in saline-treated heifers. Estrous cycle length and ovulation rate were similar for each group. In conclusion, bST increased initial development of the CL and extended its function. Furthermore, the second follicular wave was earlier with bST.

Original languageEnglish (US)
Pages (from-to)561-572
Number of pages12
JournalTheriogenology
Volume41
Issue number2
DOIs
StatePublished - 1994
Externally publishedYes

Fingerprint

Corpus Luteum
corpus luteum
somatotropin
early development
heifers
Progesterone
progesterone
Estrous Cycle
estrous cycle
bovine growth hormone
Ovarian Follicle
ovarian follicles
Estrus
Growth
Ovulation
Growth Hormone
ovulation
estrus

Keywords

  • bovine
  • corpus luteum
  • follicle
  • somatotropin

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Extended function of the corpus luteum and earlier development of the second follicular wave in heifers treated with bovine somatotropin. / Lucy, M. C.; Curran, T. L.; Collier, Robert J; Cole, W. J.

In: Theriogenology, Vol. 41, No. 2, 1994, p. 561-572.

Research output: Contribution to journalArticle

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abstract = "Effects of recombinant bovine somatotropin (bST) on growth of the corpus luteum (CL) and development of ovarian follicles were tested. Starting at estrus (Day=0), the following treatments were administered: control (saline injected Days 0 to 19, n=5); bST[0-9] (25 mg bST injected Days 0 to 9, saline injected Days 10 to 19, n=5); bST[10-19] (saline injected Days 0 to 9, 25 mg bST injected Days 10 to 19, n=5); and bST[0-19] (25 mg bST injected Days 0 to 19, n=6). Blood was collected daily for progesterone analysis, and ultrasound examinations were performed daily for measurement of follicles and CL. Compared with the heifers treated with saline, those treated with bST had larger CL and more progesterone during the early (≤ Day 10) and late (Days 15 to 21) phases of the estrous cycle. At mid-cycle (Days 10 to 15), luteal tissue area and progesterone levels were similar for bST- and saline-treated heifers. Ovarian follicular growth was similar for bST- and saline-treated heifers during the first follicular wave. However, during recruitment for the second follicular wave (Days 10 to 14), second largest follicles emerged sooner (P<0.001), the number of Class-3 (≥10 mm) follicles was greater (P<0.01) and largest follicles were smaller (P<0.001) in bST than in saline-treated heifers. Estrous cycle length and ovulation rate were similar for each group. In conclusion, bST increased initial development of the CL and extended its function. Furthermore, the second follicular wave was earlier with bST.",
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