Failure of gated single photon emission computer tomography scan to detect imminent acute plaque rupture causing acute ST-elevation myocardial infarction: Case report

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The negative predictive value of a gated single photon emission computer tomography (SPECT) scan is very high, with an event rate of < 1% in the first year. However, the presence of nonobstructive coronary artery plaque should yield normal SPECT scan findings. On the other hand, most plaque ruptures, which are a major cause of acute myocardial infarction, occur in nonobstructive coronary artery plaque. Therefore, the findings of a gated SPECT scan should be normal if a ruptured plaque has not created significant obstruction despite the imminent threat of coronary artery occlusion. We present the first case report of a documented gated SPECT scan in a patient who had experienced an acute anterior Q-wave myocardial infarction showing no significant ischemia in the anterior wall in the last minute of data acquisition.

Original languageEnglish (US)
Pages (from-to)1043-1047
Number of pages5
Issue number2
Publication statusPublished - Aug 2005
Externally publishedYes



  • Acute myocardial infarction
  • Gated single photon emission Computer Tomography
  • Myocardial perfusion
  • Plaque rupture

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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