Failure prediction and robust design of grafts for aortic aneurysms

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

The development of an abdominal aortic aneurysm (AAA) is a common condition that can lead to fatal rupture of the aorta. Endovascular repair (EVAR) is a recently implemented AAA treatment option that involves the catheterized insertion of an endoluminal graft (ELG) into the aneurysm sac to relieve pressure. Though EVAR is relatively noninvasive, it is subject to failure mechanisms including re-pressurization of the aneurysm sac as a result of leakage between the ELG and aorta (i.e. endoleak). In order to understand the influence of clinically relevant variables on the occurrence of failure, a parametric study was conducted using a finite element model capable of simulating the fluid-structure interaction inherent to the initiation of endoleak. The parameter space was explicitly decomposed into failure and non-failure regions using Support Vector Machines, a novel approach in the field of design that facilitates calculation of the probability of failure as well as robust graft design.

Original languageEnglish (US)
Title of host publicationCollection of Technical Papers - 48th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference
Pages2257-2267
Number of pages11
StatePublished - Aug 6 2007
Event48th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference - Waikiki, HI, United States
Duration: Apr 23 2007Apr 26 2007

Publication series

NameCollection of Technical Papers - AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference
Volume3
ISSN (Print)0273-4508

Other

Other48th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference
CountryUnited States
CityWaikiki, HI
Period4/23/074/26/07

ASJC Scopus subject areas

  • Architecture
  • Materials Science(all)
  • Aerospace Engineering
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Layman, R., Missoum, S., & Geest, J. V. (2007). Failure prediction and robust design of grafts for aortic aneurysms. In Collection of Technical Papers - 48th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference (pp. 2257-2267). (Collection of Technical Papers - AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference; Vol. 3).