Farm living: Effects on childhood asthma and allergy

Erika Von Mutius, Donata Vercelli

Research output: Contribution to journalArticle

370 Scopus citations

Abstract

Numerous epidemiological studies have shown that children who grow up on traditional farms are protected from asthma, hay fever and allergic sensitization. Early-life contact with livestock and their fodder, and consumption of unprocessed cow's milk have been identified as the most effective protective exposures. Studies of the immunobiology of farm living point to activation and modulation of innate and adaptive immune responses by intense microbial exposures and possibly xenogeneic signals delivered before or soon after birth.

Original languageEnglish (US)
Pages (from-to)861-868
Number of pages8
JournalNature Reviews Immunology
Volume10
Issue number12
DOIs
Publication statusPublished - Dec 2010

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ASJC Scopus subject areas

  • Immunology

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