Fate of therapy failures in adult idiopathic thrombocytopenic purpura

V. J. Picozzi, William R Roeske, W. P. Creger

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Of 38 adult patients with idiopathic thrombocytopenic purpura followed an average of more than 12 years, 15 suffered splenectomy failure or postsplenectomy recurrence of thrombocytopenia. Nine of the 15 also received immunosuppressive agents, and 4 of the 9 failed such therapy. In 8 of these 15 treatment failures normal or safe platelet counts were achieved in a subsequent 3 to 12 year period during which they received no therapy. The frequency of spontaneous recovery of satisfactory platelet levels in adults with idiopathic thrombocytopenic purpura in whom treatment failed may have negative implications for very vigorous or longstanding immunosuppressive therapeutic attempts in certain cases.

Original languageEnglish (US)
Pages (from-to)690-694
Number of pages5
JournalAmerican Journal of Medicine
Volume69
Issue number5
StatePublished - 1980
Externally publishedYes

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Idiopathic Thrombocytopenic Purpura
Immunosuppressive Agents
Splenectomy
Therapeutics
Treatment Failure
Platelet Count
Thrombocytopenia
Blood Platelets
Recurrence

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Fate of therapy failures in adult idiopathic thrombocytopenic purpura. / Picozzi, V. J.; Roeske, William R; Creger, W. P.

In: American Journal of Medicine, Vol. 69, No. 5, 1980, p. 690-694.

Research output: Contribution to journalArticle

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