Ferrying Wingless across the Synaptic Cleft

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Secreted Wnt morphogens mediate cell-cell communication, but the mechanism of Wnt transfer between cells is unknown. Korkut et al. (2009) report that the transmembrane protein Evi is a versatile carrier that guides Wingless to presynaptic terminals of motor neurons and then escorts it across the synaptic cleft. In postsynaptic muscles, Evi promotes Frizzled-2 trafficking.

Original languageEnglish (US)
Pages (from-to)229-231
Number of pages3
JournalCell
Volume139
Issue number2
DOIs
StatePublished - Oct 16 2009

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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