First in-Human Gallbladder Cryoablation in a Patient with Acute Calculous Cholecystitis Initially Treated with a Cholecystostomy Tube

Hugh McGregor; Gregory Woodhead; Miles Conrad; Andrew Tang; David Ruiz; Abdul Khan; Charles Hennemeyer

doi:10.1016/j.jvir.2018.12.011

First in-Human Gallbladder Cryoablation in a Patient with Acute Calculous Cholecystitis Initially Treated with a Cholecystostomy Tube

Hugh McGregor, Gregory Woodhead, Miles Conrad, Andrew Tang, David Ruiz, Abdul Khan, Charles Hennemeyer

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A 71-year-old poor surgical candidate with acute calculous cholecystitis was initially managed with cholecystostomy tube drainage for 28 days. He subsequently underwent gallbladder cryoablation under moderate sedation with 3 cryoprobes and 2 separate 10-8-10 freeze-thaw cycles targeting the gallbladder neck/body and fundus followed by cholecystostomy tube removal. He was discharged 1 day after ablation. Magnetic resonance and hepatobiliary iminodiacetic acid scan 1 month postablation demonstrated a thick-walled, distended gallbladder and no filling of the cystic duct. Magnetic resonance 3 months postablation demonstrated retraction of the gallbladder wall with luminal collapse. The patient denied any pain after discharge and is asymptomatic 3 months after ablation.

Original language	English (US)
Journal	Journal of Vascular and Interventional Radiology
DOIs	https://doi.org/10.1016/j.jvir.2018.12.011
State	Published - Jan 1 2019

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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First in-Human Gallbladder Cryoablation in a Patient with Acute Calculous Cholecystitis Initially Treated with a Cholecystostomy Tube. / McGregor, Hugh; Woodhead, Gregory; Conrad, Miles; Tang, Andrew; Ruiz, David; Khan, Abdul; Hennemeyer, Charles.

In: Journal of Vascular and Interventional Radiology, 01.01.2019.

Research output: Contribution to journal › Article › peer-review

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abstract = "A 71-year-old poor surgical candidate with acute calculous cholecystitis was initially managed with cholecystostomy tube drainage for 28 days. He subsequently underwent gallbladder cryoablation under moderate sedation with 3 cryoprobes and 2 separate 10-8-10 freeze-thaw cycles targeting the gallbladder neck/body and fundus followed by cholecystostomy tube removal. He was discharged 1 day after ablation. Magnetic resonance and hepatobiliary iminodiacetic acid scan 1 month postablation demonstrated a thick-walled, distended gallbladder and no filling of the cystic duct. Magnetic resonance 3 months postablation demonstrated retraction of the gallbladder wall with luminal collapse. The patient denied any pain after discharge and is asymptomatic 3 months after ablation.",

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