Fixations Gate Species-Specific Responses to Free Viewing of Faces in the Human and Macaque Amygdala

Juri Minxha, Clayton Mosher, Jeremiah K. Morrow, Adam N. Mamelak, Ralph Adolphs, Katalin M. Gothard, Ueli Rutishauser

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Neurons in the primate amygdala respond prominently to faces. This implicates the amygdala in the processing of socially significant stimuli, yet its contribution to social perception remains poorly understood. We evaluated the representation of faces in the primate amygdala during naturalistic conditions by recording from both human and macaque amygdala neurons during free viewing of identical arrays of images with concurrent eye tracking. Neurons responded to faces only when they were fixated, suggesting that neuronal activity was gated by visual attention. Further experiments in humans utilizing covert attention confirmed this hypothesis. In both species, the majority of face-selective neurons preferred faces of conspecifics, a bias also seen behaviorally in first fixation preferences. Response latencies, relative to fixation onset, were shortest for conspecific-selective neurons and were ∼100 ms shorter in monkeys compared to humans. This argues that attention to faces gates amygdala responses, which in turn prioritize species-typical information for further processing.

Original languageEnglish (US)
Pages (from-to)878-891
Number of pages14
JournalCell Reports
Volume18
Issue number4
DOIs
StatePublished - Jan 24 2017

Keywords

  • amygdala
  • attention
  • face cells
  • human single neuron
  • interspecies comparison
  • latency
  • visual tuning

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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