Flavonoids: From cell cycle regulation to biotechnology

Ho Hyung Woo, Byeong Ryong Jeong, Martha C Hawes

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Flavonoids have been proposed to play diverse roles in plant growth and development, including defense, symbiosis, pollen development and male fertility, polar auxin transport, and protection against ultraviolet radiation. Recently, a new role in cell cycle regulation has emerged. Genetic alteration of glucuronide metabolism by altered expression of a Pisum sativum UDP-glucuronosyltransferase (PsUGT1) results in an altered cell cycle in pea, alfalfa, and Arabidopsis. In alfalfa, altered expression of PsUGT1 results in accumulation of a flavonoid-like compound that suppresses growth of cultured cells. The results are consistent with the hypothesis that PsUGT1 functions by controlling cellular levels of a factor controlling cell cycle (FCC).

Original languageEnglish (US)
Pages (from-to)365-374
Number of pages10
JournalBiotechnology Letters
Volume27
Issue number6
DOIs
StatePublished - Mar 2005

Fingerprint

Flavonoids
Biotechnology
Cell Cycle
Medicago sativa
Peas
Cells
Glucuronosyltransferase
Indoleacetic Acids
Plant Development
Symbiosis
Glucuronides
Pollen
Growth and Development
Arabidopsis
Fertility
Cultured Cells
Metabolism
Ultraviolet radiation
Radiation
Growth

Keywords

  • Cell cycle regulation
  • Flavonoids
  • UDP-glucuronosyltransferase

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Bioengineering

Cite this

Flavonoids : From cell cycle regulation to biotechnology. / Woo, Ho Hyung; Jeong, Byeong Ryong; Hawes, Martha C.

In: Biotechnology Letters, Vol. 27, No. 6, 03.2005, p. 365-374.

Research output: Contribution to journalArticle

Woo, Ho Hyung ; Jeong, Byeong Ryong ; Hawes, Martha C. / Flavonoids : From cell cycle regulation to biotechnology. In: Biotechnology Letters. 2005 ; Vol. 27, No. 6. pp. 365-374.
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