Flow-dependent mechanics of red blood cell motion in a capillary with an endothelial surface layer

Timothy W. Secomb, Richard Hsu, Axel R. Pries

Research output: Contribution to journalConference articlepeer-review

Abstract

A theoretical model is used to investigate the effects of flow velocity on the motion of red blood cells in a capillary with an ESL. Cell deformation is analyzed including effects of membrane shear and bending elasticity. Axisymmetric red cell shapes are assumed. The model shows that exclusion of red blood cells from the ESL in flowing capillaries can result from hydrodynamic forces generated by plasma flow through the ESL.

Original languageEnglish (US)
Pages (from-to)S-71
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'Flow-dependent mechanics of red blood cell motion in a capillary with an endothelial surface layer'. Together they form a unique fingerprint.

Cite this