FMRI activation in language areas correlates with verb generation performance in children

J. Vannest, J. Rasmussen, K. P. Eaton, K. Patel, V. Schmithorst, P. Karunanayaka, Elena M Plante, A. Byars, S. Holland

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Functional MRI mapping of language areas in children frequently employs a covert verb generation task. Because responses are not monitored, the relationship between fMRI activation and task performance is unknown. We compared fMRI activation during covert and overt verb generation to performance during the overt task. 15 children, ages 11-13 years, listened to concrete nouns and responded with related verbs covertly and overtly. A clustered fMRI acquisition allowed for recording of overt responses without motion artifacts. Region of interest analysis was also performed in areas that exhibited correlation between activation and performance during overt verb generation in left inferior frontal and left superior temporal gyri (along with their right hemisphere homologues). Regression analysis determined that during both covert and overt generation, left hemisphere regions showed positive correlations with average counts of verbs generated during the overt task. These results suggest that increased verb generation performance leads to increased activation. In addition, overt performance may be used as an estimator of covert performance.

Original languageEnglish (US)
Pages (from-to)235-239
Number of pages5
JournalNeuropediatrics
Volume41
Issue number5
DOIs
StatePublished - 2010

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Language
Magnetic Resonance Imaging
Task Performance and Analysis
Temporal Lobe
Artifacts
Regression Analysis

Keywords

  • functional MRI
  • language lateralization
  • language skill

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Vannest, J., Rasmussen, J., Eaton, K. P., Patel, K., Schmithorst, V., Karunanayaka, P., ... Holland, S. (2010). FMRI activation in language areas correlates with verb generation performance in children. Neuropediatrics, 41(5), 235-239. https://doi.org/10.1055/s-0030-1267982

FMRI activation in language areas correlates with verb generation performance in children. / Vannest, J.; Rasmussen, J.; Eaton, K. P.; Patel, K.; Schmithorst, V.; Karunanayaka, P.; Plante, Elena M; Byars, A.; Holland, S.

In: Neuropediatrics, Vol. 41, No. 5, 2010, p. 235-239.

Research output: Contribution to journalArticle

Vannest, J, Rasmussen, J, Eaton, KP, Patel, K, Schmithorst, V, Karunanayaka, P, Plante, EM, Byars, A & Holland, S 2010, 'FMRI activation in language areas correlates with verb generation performance in children', Neuropediatrics, vol. 41, no. 5, pp. 235-239. https://doi.org/10.1055/s-0030-1267982
Vannest J, Rasmussen J, Eaton KP, Patel K, Schmithorst V, Karunanayaka P et al. FMRI activation in language areas correlates with verb generation performance in children. Neuropediatrics. 2010;41(5):235-239. https://doi.org/10.1055/s-0030-1267982
Vannest, J. ; Rasmussen, J. ; Eaton, K. P. ; Patel, K. ; Schmithorst, V. ; Karunanayaka, P. ; Plante, Elena M ; Byars, A. ; Holland, S. / FMRI activation in language areas correlates with verb generation performance in children. In: Neuropediatrics. 2010 ; Vol. 41, No. 5. pp. 235-239.
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