Abstract
Functional MRI mapping of language areas in children frequently employs a covert verb generation task. Because responses are not monitored, the relationship between fMRI activation and task performance is unknown. We compared fMRI activation during covert and overt verb generation to performance during the overt task. 15 children, ages 11-13 years, listened to concrete nouns and responded with related verbs covertly and overtly. A clustered fMRI acquisition allowed for recording of overt responses without motion artifacts. Region of interest analysis was also performed in areas that exhibited correlation between activation and performance during overt verb generation in left inferior frontal and left superior temporal gyri (along with their right hemisphere homologues). Regression analysis determined that during both covert and overt generation, left hemisphere regions showed positive correlations with average counts of verbs generated during the overt task. These results suggest that increased verb generation performance leads to increased activation. In addition, overt performance may be used as an estimator of covert performance.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 235-239 |
| Number of pages | 5 |
| Journal | Neuropediatrics |
| Volume | 41 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2010 |
Fingerprint
Keywords
- functional MRI
- language lateralization
- language skill
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
FMRI activation in language areas correlates with verb generation performance in children. / Vannest, J.; Rasmussen, J.; Eaton, K. P.; Patel, K.; Schmithorst, V.; Karunanayaka, P.; Plante, Elena M; Byars, A.; Holland, S.
In: Neuropediatrics, Vol. 41, No. 5, 2010, p. 235-239.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - FMRI activation in language areas correlates with verb generation performance in children
AU - Vannest, J.
AU - Rasmussen, J.
AU - Eaton, K. P.
AU - Patel, K.
AU - Schmithorst, V.
AU - Karunanayaka, P.
AU - Plante, Elena M
AU - Byars, A.
AU - Holland, S.
PY - 2010
Y1 - 2010
N2 - Functional MRI mapping of language areas in children frequently employs a covert verb generation task. Because responses are not monitored, the relationship between fMRI activation and task performance is unknown. We compared fMRI activation during covert and overt verb generation to performance during the overt task. 15 children, ages 11-13 years, listened to concrete nouns and responded with related verbs covertly and overtly. A clustered fMRI acquisition allowed for recording of overt responses without motion artifacts. Region of interest analysis was also performed in areas that exhibited correlation between activation and performance during overt verb generation in left inferior frontal and left superior temporal gyri (along with their right hemisphere homologues). Regression analysis determined that during both covert and overt generation, left hemisphere regions showed positive correlations with average counts of verbs generated during the overt task. These results suggest that increased verb generation performance leads to increased activation. In addition, overt performance may be used as an estimator of covert performance.
AB - Functional MRI mapping of language areas in children frequently employs a covert verb generation task. Because responses are not monitored, the relationship between fMRI activation and task performance is unknown. We compared fMRI activation during covert and overt verb generation to performance during the overt task. 15 children, ages 11-13 years, listened to concrete nouns and responded with related verbs covertly and overtly. A clustered fMRI acquisition allowed for recording of overt responses without motion artifacts. Region of interest analysis was also performed in areas that exhibited correlation between activation and performance during overt verb generation in left inferior frontal and left superior temporal gyri (along with their right hemisphere homologues). Regression analysis determined that during both covert and overt generation, left hemisphere regions showed positive correlations with average counts of verbs generated during the overt task. These results suggest that increased verb generation performance leads to increased activation. In addition, overt performance may be used as an estimator of covert performance.
KW - functional MRI
KW - language lateralization
KW - language skill
UR - http://www.scopus.com/inward/record.url?scp=78650994498&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650994498&partnerID=8YFLogxK
U2 - 10.1055/s-0030-1267982
DO - 10.1055/s-0030-1267982
M3 - Article
C2 - 21210340
AN - SCOPUS:78650994498
VL - 41
SP - 235
EP - 239
JO - Neuropediatrics
JF - Neuropediatrics
SN - 0174-304X
IS - 5
ER -