Frequency of resistance to Bacillus thuringiensis in field populations of pink bollworm

Bruce E. Tabashnik, Amanda L. Patin, Timothy J. Dennehy, Yong Biao Liu, Yves Carrière, Maria A. Sims, Larry Antilla

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Abstract

Strategies for delaying pest resistance to genetically modified crops that produce Bacillus thuringiensis (Bt) toxins are based primarily on theoretical models. One key assumption of such models is that genes conferring resistance are rare. Previous estimates for lepidopteran pests targeted by St crops seem to meet this assumption. We report here that the estimated frequency of a recessive allele conferring resistance to Bt toxin Cry1Ac was 0.16 (95% confidence interval = 0.05-0.26) in strains of pink bollworm (Pectinophora gossypiella) derived from 10 Arizona cotton fields during 1997. Unexpectedly, the estimated resistance allele frequency did not increase from 1997 to 1999 and St cotton remained extremely effective against pink bollworm. These results demonstrate that the assumptions and predictions of resistance management models must be reexamined.

Original languageEnglish (US)
Pages (from-to)12980-12984
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume97
Issue number24
DOIs
StatePublished - Nov 21 2000

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