From genomics to mechanistic insight: A global perspective on molecular deficits induced by environmental agents

Kenneth Ramos, Marlene C. Steffen, M. H. Falahatpisheh, Adrian Nanez

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

As the postgenomic era continues to unfold, a new wave of scientific investigation is upon us focusing on the application of genomic technologies to study the meanings encrypted on the DNA code and the responses of living organisms to changes in their environment. Recent functional genomics studies in this laboratory have focused on the role of the aryl hydrocarbon receptor, a ubiquitous transcription factor, in genetic programming during renal development. Also of interest is the application of genomics investigations to the study of chronic medical conditions associated with early life exposures to environmental contaminants. Molecular evidence is discussed in this review within the framework of human molecular medicine.

Original languageEnglish (US)
Pages (from-to)395-399
Number of pages5
JournalEnvironmental and Molecular Mutagenesis
Volume48
Issue number5
DOIs
StatePublished - Jun 2007
Externally publishedYes

Fingerprint

global perspective
Genomics
genomics
Molecular Medicine
Aryl Hydrocarbon Receptors
Genetic programming
Environmental Exposure
Medicine
Transcription Factors
Impurities
Technology
Kidney
medicine
DNA
hydrocarbon
pollutant

Keywords

  • Aryl hydrocarbon receptor
  • Molecular medicine
  • Nephrogenesis

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry
  • Genetics
  • Genetics(clinical)
  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

From genomics to mechanistic insight : A global perspective on molecular deficits induced by environmental agents. / Ramos, Kenneth; Steffen, Marlene C.; Falahatpisheh, M. H.; Nanez, Adrian.

In: Environmental and Molecular Mutagenesis, Vol. 48, No. 5, 06.2007, p. 395-399.

Research output: Contribution to journalArticle

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