From quantal counts to mechanisms and systems: The past, present, and future of biometrics in environmental toxicology

A. John Bailer, Walter W Piegorsch

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

As appreciation for human impact on the environment has developed, so have the experimental systems and associated statistical tools that quantify this impact. Toxicological study in particular has grown in its complexity and its need for advanced statistical support. Within this perspective, we describe statistical practice in environmental toxicology and risk assessment. We present two case studies, one from mammalian toxicology and one from aquatic toxicology, that highlight the evolution of statistical practice in environmental toxicology.

Original languageEnglish (US)
Pages (from-to)327-336
Number of pages10
JournalBiometrics
Volume56
Issue number2
StatePublished - Jun 2000
Externally publishedYes

Fingerprint

Ecotoxicology
Toxicology
ecotoxicology
toxicology
Biometrics
biometry
Count
Risk assessment
risk assessment
anthropogenic activities
case studies
Risk Assessment
Quantify

Keywords

  • Aquatic toxicology
  • Concentration-response modeling
  • Dose-response modeling
  • Ecotoxicology
  • Environmental carcinogenesis
  • Environmental health
  • Environmental statistics
  • Environmetrics
  • Interdisciplinary collaboration
  • NOEC
  • NOEL
  • Potency estimation
  • Quantitative risk assessment
  • Response inhibition
  • Risk analysis
  • Stochastic modeling
  • Trend tests

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Public Health, Environmental and Occupational Health
  • Agricultural and Biological Sciences (miscellaneous)
  • Applied Mathematics
  • Statistics and Probability

Cite this

From quantal counts to mechanisms and systems : The past, present, and future of biometrics in environmental toxicology. / Bailer, A. John; Piegorsch, Walter W.

In: Biometrics, Vol. 56, No. 2, 06.2000, p. 327-336.

Research output: Contribution to journalArticle

@article{368a615a8dcc4d3984a50df305419682,
title = "From quantal counts to mechanisms and systems: The past, present, and future of biometrics in environmental toxicology",
abstract = "As appreciation for human impact on the environment has developed, so have the experimental systems and associated statistical tools that quantify this impact. Toxicological study in particular has grown in its complexity and its need for advanced statistical support. Within this perspective, we describe statistical practice in environmental toxicology and risk assessment. We present two case studies, one from mammalian toxicology and one from aquatic toxicology, that highlight the evolution of statistical practice in environmental toxicology.",
keywords = "Aquatic toxicology, Concentration-response modeling, Dose-response modeling, Ecotoxicology, Environmental carcinogenesis, Environmental health, Environmental statistics, Environmetrics, Interdisciplinary collaboration, NOEC, NOEL, Potency estimation, Quantitative risk assessment, Response inhibition, Risk analysis, Stochastic modeling, Trend tests",
author = "Bailer, {A. John} and Piegorsch, {Walter W}",
year = "2000",
month = "6",
language = "English (US)",
volume = "56",
pages = "327--336",
journal = "Biometrics",
issn = "0006-341X",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - From quantal counts to mechanisms and systems

T2 - The past, present, and future of biometrics in environmental toxicology

AU - Bailer, A. John

AU - Piegorsch, Walter W

PY - 2000/6

Y1 - 2000/6

N2 - As appreciation for human impact on the environment has developed, so have the experimental systems and associated statistical tools that quantify this impact. Toxicological study in particular has grown in its complexity and its need for advanced statistical support. Within this perspective, we describe statistical practice in environmental toxicology and risk assessment. We present two case studies, one from mammalian toxicology and one from aquatic toxicology, that highlight the evolution of statistical practice in environmental toxicology.

AB - As appreciation for human impact on the environment has developed, so have the experimental systems and associated statistical tools that quantify this impact. Toxicological study in particular has grown in its complexity and its need for advanced statistical support. Within this perspective, we describe statistical practice in environmental toxicology and risk assessment. We present two case studies, one from mammalian toxicology and one from aquatic toxicology, that highlight the evolution of statistical practice in environmental toxicology.

KW - Aquatic toxicology

KW - Concentration-response modeling

KW - Dose-response modeling

KW - Ecotoxicology

KW - Environmental carcinogenesis

KW - Environmental health

KW - Environmental statistics

KW - Environmetrics

KW - Interdisciplinary collaboration

KW - NOEC

KW - NOEL

KW - Potency estimation

KW - Quantitative risk assessment

KW - Response inhibition

KW - Risk analysis

KW - Stochastic modeling

KW - Trend tests

UR - http://www.scopus.com/inward/record.url?scp=0033946571&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033946571&partnerID=8YFLogxK

M3 - Article

C2 - 10877286

AN - SCOPUS:0033946571

VL - 56

SP - 327

EP - 336

JO - Biometrics

JF - Biometrics

SN - 0006-341X

IS - 2

ER -