Functional chromatographic technique for natural product isolation

Eric C. Lau, Damian J. Mason, Nicole Eichhorst, Pearce Engelder, Celestina Mesa, E. M. Kithsiri Wijeratne, G. M.Kamal B. Gunaherath, A. A.Leslie Gunatilaka, James J. La Clair, Eli Chapman

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation. This journal is

Original languageEnglish (US)
Pages (from-to)2255-2259
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number8
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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  • Cite this

    Lau, E. C., Mason, D. J., Eichhorst, N., Engelder, P., Mesa, C., Kithsiri Wijeratne, E. M., Gunaherath, G. M. K. B., Gunatilaka, A. A. L., La Clair, J. J., & Chapman, E. (2015). Functional chromatographic technique for natural product isolation. Organic and Biomolecular Chemistry, 13(8), 2255-2259. https://doi.org/10.1039/c4ob02292k