Functional interactions between opioid mu and delta receptors in vivo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recent work has shown that δ agonists, given at dose which do not produce antinociception, increase or decrease the antinociceptive potency and efficacy of some μ agonists such as morphine without altering the rate of development of tolerance. Such studies in vivo, and others in vitro, form the basis of a hypothesis of functionally complexed μ and δ receptors. Compounds with apparent selectivity for these sites are being identified.

Original languageEnglish (US)
Title of host publicationNew leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914
EditorsJ.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
PublisherElsevier Science Publishers B.V.
Pages280
Number of pages1
ISBN (Print)044481213X
StatePublished - 1990
EventThe International Narcotics Research Conference -
Duration: Jul 8 1989Jul 13 1989

Other

OtherThe International Narcotics Research Conference
Period7/8/897/13/89

Fingerprint

delta Opioid Receptor
mu Opioid Receptor
Morphine
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Porreca, F. (1990). Functional interactions between opioid mu and delta receptors in vivo. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, ... T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (pp. 280). Elsevier Science Publishers B.V..

Functional interactions between opioid mu and delta receptors in vivo. / Porreca, Frank.

New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. ed. / J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus; J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. p. 280.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Porreca, F 1990, Functional interactions between opioid mu and delta receptors in vivo. in JM Van Ree, AH Mulder, VM Wiegant, TB Van Wimersma Greidanus, JM Van Ree, AH Mulder, VM Wiegant & TB Van Wimersma Greidanus (eds), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Elsevier Science Publishers B.V., pp. 280, The International Narcotics Research Conference, 7/8/89.
Porreca F. Functional interactions between opioid mu and delta receptors in vivo. In Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, editors, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Elsevier Science Publishers B.V. 1990. p. 280
Porreca, Frank. / Functional interactions between opioid mu and delta receptors in vivo. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. editor / J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus ; J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. pp. 280
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