Fungal Endocarditis: Update on Diagnosis and Management

Ahmed Khurshid Pasha, Justin Z. Lee, See Wei Low, Hem Desai, Kwan S Lee, Mayar Al Mohajer

Research output: Contribution to journalReview article

19 Scopus citations

Abstract

Fungal endocarditis is an extremely debilitating disease associated with high morbidity and mortality. Candida spp. are the most common isolated organisms in fungal endocarditis. It is most prevalent in patients who are immunosuppressed and intravenous drug users. Most patients present with constitutional symptoms, which are indistinguishable from bacterial endocarditis, hence a high index of suspicion is required for pursuing diagnosis. Diagnosis of fungal endocarditis can be very challenging: most of the time, blood cultures are negative or take a long time to yield growth. Fungal endocarditis mandates an aggressive treatment strategy. A medical and surgical combined approach is the cornerstone of therapy.

Original languageEnglish (US)
Pages (from-to)1037-1043
Number of pages7
JournalAmerican Journal of Medicine
Volume129
Issue number10
DOIs
StatePublished - Oct 1 2016

Keywords

  • Aspergillus
  • Candida
  • Emboli
  • Endocarditis
  • Fungal

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Pasha, A. K., Lee, J. Z., Low, S. W., Desai, H., Lee, K. S., & Al Mohajer, M. (2016). Fungal Endocarditis: Update on Diagnosis and Management. American Journal of Medicine, 129(10), 1037-1043. https://doi.org/10.1016/j.amjmed.2016.05.012