Gene ontology consortium: Going forward

Gene Ontology Consortium

Research output: Contribution to journalArticle

1340 Scopus citations

Abstract

The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community. The Gene Ontology Consortium (GOC) has expanded areas of the ontology such as cilia-related terms, cell-cycle terms and multicellular organism processes. We have also implemented new tools for generating ontology terms based on a set of logical rules making use of templates, and we have made efforts to increase our use of logical definitions. The GOC has a new and improved web site summarizing new developments and documentation, serving as a portal to GO data. Users can perform GO enrichment analysis, and search the GO for terms, annotations to gene products, and associated metadata across multiple species using the all-new AmiGO2 browser. We encourage and welcome the input of the research community in all biological areas in our continued effort to improve the Gene Ontology.

Original languageEnglish (US)
Pages (from-to)D1049-D1056
JournalNucleic Acids Research
Volume43
Issue numberD1
DOIs
Publication statusPublished - Jan 28 2015
Externally publishedYes

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ASJC Scopus subject areas

  • Genetics

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