Generation of the [NiFe] hydrogenase active site (sulfur's the one!)

Richard S Glass, Athanasios Paschos, Stephanie Reissmann, M. S. Singh, Haofan Wang, August Böck

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Chemical and biochemical methods were used to unravel the unprecedented pathway by which the CN ligands of iron in [NiFe] hydrogenase are introduced. Carbamoyl phosphate is the one carbon precursor of these ligands, and reactions involving a protein cysteinyl sulfur are key for processing this precursor into CN ligands.

Original languageEnglish (US)
Pages (from-to)1183-1195
Number of pages13
JournalPhosphorus, Sulfur and Silicon and Related Elements
Volume180
Issue number5-6
DOIs
StatePublished - May 2005

Fingerprint

Sulfur
Catalytic Domain
Ligands
Carbamyl Phosphate
Carbon
Iron
Processing
nickel-iron hydrogenase
Proteins

Keywords

  • [NiFe] hydrogenase biosynthesis
  • Carbamoyl phosphate
  • Thiocarbamate, thiocyanate

ASJC Scopus subject areas

  • Inorganic Chemistry

Cite this

Generation of the [NiFe] hydrogenase active site (sulfur's the one!). / Glass, Richard S; Paschos, Athanasios; Reissmann, Stephanie; Singh, M. S.; Wang, Haofan; Böck, August.

In: Phosphorus, Sulfur and Silicon and Related Elements, Vol. 180, No. 5-6, 05.2005, p. 1183-1195.

Research output: Contribution to journalArticle

Glass, Richard S ; Paschos, Athanasios ; Reissmann, Stephanie ; Singh, M. S. ; Wang, Haofan ; Böck, August. / Generation of the [NiFe] hydrogenase active site (sulfur's the one!). In: Phosphorus, Sulfur and Silicon and Related Elements. 2005 ; Vol. 180, No. 5-6. pp. 1183-1195.
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