Abstract
Phytopathogens coordinate multifaceted life histories and deploy stratified virulence determinants via complex, global regulation networks. We dissect the global regulation of four distantly related model phytopathogens to evaluate large-scale events and mechanisms that determine successful pathogenesis. Overarching themes include dependence on centralized cell-to-cell communication systems, pervasive two-component signal-transduction systems, post-transcriptional regulation systems, AraC-like regulators and sigma factors. Although these common regulatory systems control virulence, each functions in different capacities, and to differing ends, in the diverse species. Hence, the virulence regulation network of each species determines its survival and success in various life histories and niches.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 363-371 |
| Number of pages | 9 |
| Journal | Trends in Microbiology |
| Volume | 15 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Infectious Diseases
- Microbiology
Cite this
Global virulence regulation networks in phytopathogenic bacteria. / Mole, Beth M.; Baltrus, David A; Dangl, Jeffery L.; Grant, Sarah R.
In: Trends in Microbiology, Vol. 15, No. 8, 08.2007, p. 363-371.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Global virulence regulation networks in phytopathogenic bacteria
AU - Mole, Beth M.
AU - Baltrus, David A
AU - Dangl, Jeffery L.
AU - Grant, Sarah R.
PY - 2007/8
Y1 - 2007/8
N2 - Phytopathogens coordinate multifaceted life histories and deploy stratified virulence determinants via complex, global regulation networks. We dissect the global regulation of four distantly related model phytopathogens to evaluate large-scale events and mechanisms that determine successful pathogenesis. Overarching themes include dependence on centralized cell-to-cell communication systems, pervasive two-component signal-transduction systems, post-transcriptional regulation systems, AraC-like regulators and sigma factors. Although these common regulatory systems control virulence, each functions in different capacities, and to differing ends, in the diverse species. Hence, the virulence regulation network of each species determines its survival and success in various life histories and niches.
AB - Phytopathogens coordinate multifaceted life histories and deploy stratified virulence determinants via complex, global regulation networks. We dissect the global regulation of four distantly related model phytopathogens to evaluate large-scale events and mechanisms that determine successful pathogenesis. Overarching themes include dependence on centralized cell-to-cell communication systems, pervasive two-component signal-transduction systems, post-transcriptional regulation systems, AraC-like regulators and sigma factors. Although these common regulatory systems control virulence, each functions in different capacities, and to differing ends, in the diverse species. Hence, the virulence regulation network of each species determines its survival and success in various life histories and niches.
UR - http://www.scopus.com/inward/record.url?scp=34547176755&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34547176755&partnerID=8YFLogxK
U2 - 10.1016/j.tim.2007.06.005
DO - 10.1016/j.tim.2007.06.005
M3 - Article
C2 - 17627825
AN - SCOPUS:34547176755
VL - 15
SP - 363
EP - 371
JO - Trends in Microbiology
JF - Trends in Microbiology
SN - 0966-842X
IS - 8
ER -