Gonyauline: A novel endogenous substance shortening the period of the circadian clock of a unicellular alga

T. Roenneberg, H. Nakamura, Lee D Cranmer, K. Ryan, Y. Kishi, J. W. Hastings

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The circadian clock in the unicellular alga Gonyaulax polyedra is accelerated by a substance in extracts from the cells themselves. The extracts have been fractionated using the circadian rhythm of bioluminescence as bioassay. The active substance, termed gonyauline, has been isolated and characterized as a novel low molecular weight cyclopropanecarboxylic acid (S-methyl-cis-2-(methylthio) cyclopropanecarboxylic acid). Synthetic gonyauline has a similar shortening effect on the period of the circadian clock.

Original languageEnglish (US)
Pages (from-to)103-106
Number of pages4
JournalExperientia
Volume47
Issue number1
DOIs
StatePublished - Jan 1991
Externally publishedYes

Fingerprint

Circadian Clocks
Algae
Clocks
Bioluminescence
Dinoflagellida
Bioassay
Circadian Rhythm
Cell Extracts
Biological Assay
Molecular Weight
Molecular weight
Acids
gonyauline

Keywords

  • Circadian rhythm
  • creatine
  • Gonyaulax polyedra
  • period length
  • S-methyl-cis-2-(methylthio) cyclopropanecarboxylic acid

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Gonyauline : A novel endogenous substance shortening the period of the circadian clock of a unicellular alga. / Roenneberg, T.; Nakamura, H.; Cranmer, Lee D; Ryan, K.; Kishi, Y.; Hastings, J. W.

In: Experientia, Vol. 47, No. 1, 01.1991, p. 103-106.

Research output: Contribution to journalArticle

Roenneberg, T. ; Nakamura, H. ; Cranmer, Lee D ; Ryan, K. ; Kishi, Y. ; Hastings, J. W. / Gonyauline : A novel endogenous substance shortening the period of the circadian clock of a unicellular alga. In: Experientia. 1991 ; Vol. 47, No. 1. pp. 103-106.
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