Gonyauline: A novel endogenous substance shortening the period of the circadian clock of a unicellular alga

T. Roenneberg, H. Nakamura, L. D. Cranmer, K. Ryan, Y. Kishi, J. W. Hastings

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

The circadian clock in the unicellular alga Gonyaulax polyedra is accelerated by a substance in extracts from the cells themselves. The extracts have been fractionated using the circadian rhythm of bioluminescence as bioassay. The active substance, termed gonyauline, has been isolated and characterized as a novel low molecular weight cyclopropanecarboxylic acid (S-methyl-cis-2-(methylthio) cyclopropanecarboxylic acid). Synthetic gonyauline has a similar shortening effect on the period of the circadian clock.

Original languageEnglish (US)
Pages (from-to)103-106
Number of pages4
JournalExperientia
Volume47
Issue number1
DOIs
StatePublished - Jan 1 1991

Keywords

  • Circadian rhythm
  • Gonyaulax polyedra
  • S-methyl-cis-2-(methylthio) cyclopropanecarboxylic acid
  • creatine
  • period length

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Gonyauline: A novel endogenous substance shortening the period of the circadian clock of a unicellular alga'. Together they form a unique fingerprint.

Cite this