Granulocyte-Stimulating Factor-Induced Bone Marrow Reconversion Simulating Neuroblastoma Metastases on MRI: Case Report and Literature Review

Jason C. Naples, Mihra Taljanovic, Michael L. Graham, Tim B. Hunter

Research output: Contribution to journalArticle

3 Scopus citations


Granulocyte colony-stimulating factor (GCSF), often used as an adjunct to chemotherapy, can pose a dilemma in differentiating the associated bone marrow changes from metastatic disease on magnetic resonance imaging. The phenomenon has been previously reported in children undergoing treatment for primary musculoskeletal malignancies [. 1, 2]. We present a case of GCSF-induced marrow reconversion simulating neuroblastoma metastases on MR imaging. An interesting observation in our case was intense abnormal signal in a pattern of metaphyseal bands, which, to our knowledge, was not previously reported in the English literature to be associated with GCSF-induced marrow reconversion.

Original languageEnglish (US)
Article number24
JournalRadiology Case Reports
Issue number1
Publication statusPublished - 2007


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this