Halicylindrosides, antifungal and cytotoxic cerebrosides from the marine sponge Halichondria cylindrata

Hong yu Li, Shigeki Matsunaga, Nobuhiro Fusetani

Research output: Contribution to journalArticle

67 Scopus citations

Abstract

Ten new glycosphingolipids, halicylindrosides A1-A4 (1-4) and B1-B6 (5-10) have been isolated from the Japanese marine sponge Halichondria cylindrata. Their structures were determined by spectroscopic and chemical methods. These cerebrosides were moderately antifungal against Mortierella remanniana, and cytotoxic against P388 murine leukemia cells.

Original languageEnglish (US)
Pages (from-to)2273-2280
Number of pages8
JournalTetrahedron
Volume51
Issue number8
DOIs
StatePublished - Feb 20 1995

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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