Hemodynamic and two-phase material properties of the arterial wall in rats with heart failure

Mohamed A. Gaballa, Thomas E. Raya, Bruce R. Simon, Steven Goldman

Research output: Contribution to conferencePaperpeer-review

1 Scopus citations

Abstract

Hemodynamic, passive material properties and water permeability of the carotid artery were measured in rats with heart failure produced by ligation of the coronary artery. These measurements were implemented into finite element models based on large deformation, two-phase theory. Heart failure resulted in a decrease in the radial total stress gradient across the arterial wall and an increase in the circumferential stress gradient. Treatment with captopril bur not hydralazine decrease the steady state wall stress gradients.

Original languageEnglish (US)
Pages3-4
Number of pages2
StatePublished - Dec 1 1994
Externally publishedYes
EventProceedings of the 1994 International Mechanical Engineering Congress and Exposition - Chicago, IL, USA
Duration: Nov 6 1994Nov 11 1994

Other

OtherProceedings of the 1994 International Mechanical Engineering Congress and Exposition
CityChicago, IL, USA
Period11/6/9411/11/94

ASJC Scopus subject areas

  • Engineering(all)

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