Hemodynamic effects of high-frequency jet ventilation

C. W. Otto, S. F. Quan, T. J. Conahan, J. M. Calkins, C. K. Waterson, S. R. Hameroff

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The hemodynamic effects of high-frequency jet ventilation (HFJV) and conventional ventilation were compared in normovolemic and functionally hypovolemic dogs. In normovolemic animals, no differences in hemodynamic function were found among spontaneous ventilation, conventional ventilation, and HFJV. When venous return was impaired by 15 cm H 2O PEEP, cardiac index and stroke index were 25% higher with HFJV than with conventional ventilation (P<0.05). In another study with PEEP, conventional ventilation was compared to spontaneous ventilation, HFJV synchronized to five different parts of the cardiac cycle, and asynchronous HFJV. Heart rate was 15% lower and mean arterial pressure was 26% lower with conventional ventilation than with HFJV modes (P<0.05). There were no differences between synchronous and asynchronous HFJV. These results indicate that hemodynamic dysfunction may be less likely with HFJV than conventional ventilation. No advantage of synchronizing jet pulsations to a specific part of the cardiac cycle could be demonstrated.

Original languageEnglish (US)
Pages (from-to)298-304
Number of pages7
JournalAnesthesia and analgesia
Volume62
Issue number3
StatePublished - May 5 1983

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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