Hemodynamics and Vascular Remodeling

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The flow of blood in the vasculature generates forces that act on vessel walls. Blood pressure generates circumferential stresses within the walls, while the endothelial lining of vessels experiences shear stresses as a consequence of blood’s motion over it. Both types of stress can elicit biological responses from cells in the walls, including growth and remodeling that are required for the normal function of the vasculature, and the development of vascular diseases. The main objective of this review is to summarize the dynamical features of blood flow as they affect the stresses that act on vessel walls. A second objective is to summarize the relationship between these stresses and the resulting structural responses in normal and disease states.

Original languageEnglish (US)
Title of host publicationCardiac and Vascular Biology
PublisherSpringer Science and Business Media Deutschland GmbH
Pages1-20
Number of pages20
DOIs
StatePublished - 2021

Publication series

NameCardiac and Vascular Biology
Volume8
ISSN (Print)2509-7830
ISSN (Electronic)2509-7849

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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