Hemolysis due to Chemical Contamination of Clinical Perfusion Apparatus

Douglas F. Larson, Bruce Mayall, Robert M. Anderson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A chemical contaminant found on the interior surface of the extracorporeal apparatus manufactured by the William Harvey Corporation was believed to have caused severe hematuria in 2 children. The biological activity of the contaminant was tested by mixing 50 ml of whole blood in contaminated cardiotomies; after 5 minutes of exposure lysis of one-sixth of the red blood cells was found. This hemolytic agent was concluded to be bisphenol A dissolved in an organic solvent, but the mechanism of contamination was never found.

Original languageEnglish (US)
Pages (from-to)374-375
Number of pages2
JournalAnnals of Thoracic Surgery
Volume23
Issue number4
DOIs
StatePublished - Jan 1 1977

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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