Heparin-induced thrombocytopenia

An iatrogenic catastrophe

Elisabeth L. Dupont, Vivian Gahtan, Joseph L Mills

Research output: Contribution to journalArticle

Abstract

Serious limb- and life-threatening thromboembolic complications may result from immune-mediated, heparin-induced thrombocytopenia (HIT) type II. The authors describe three such cases associated with devastating outcomes. The clinical diagnosis of HIT II was based on (1) falling platelet count on heparin (<150,000/mm3), (2) thromboembolic events on heparin, and (3) absence of new thrombotic events after heparin discontinuation. These distinct case presentations are discussed to broaden clinical awareness of HIT II. A high index of suspicion is warranted to prevent this catastrophic complication.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalVascular Surgery
Volume33
Issue number1
StatePublished - Jan 1999

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Thrombocytopenia
Heparin
Platelet Count
Extremities

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Heparin-induced thrombocytopenia : An iatrogenic catastrophe. / Dupont, Elisabeth L.; Gahtan, Vivian; Mills, Joseph L.

In: Vascular Surgery, Vol. 33, No. 1, 01.1999, p. 43-49.

Research output: Contribution to journalArticle

Dupont, EL, Gahtan, V & Mills, JL 1999, 'Heparin-induced thrombocytopenia: An iatrogenic catastrophe', Vascular Surgery, vol. 33, no. 1, pp. 43-49.
Dupont, Elisabeth L. ; Gahtan, Vivian ; Mills, Joseph L. / Heparin-induced thrombocytopenia : An iatrogenic catastrophe. In: Vascular Surgery. 1999 ; Vol. 33, No. 1. pp. 43-49.
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