Hepatic toxicity of Vitamin A and synthetic retinoids

MICHAEL B. FALLON, JAMES L. BOYER

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side‐effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids.

Original languageEnglish (US)
Pages (from-to)334-342
Number of pages9
JournalJournal of Gastroenterology and Hepatology
Volume5
Issue number3
DOIs
StatePublished - Jun 1990
Externally publishedYes

Keywords

  • Key words:
  • Vitamin A.
  • etretinate
  • isotretinoin
  • liver
  • retinol
  • synthetic retinoids

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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