Hepatitis C virus in Mexican Americans: A population-based study reveals relatively high prevalence and negative association with diabetes

G. P. Watt, K. P. Vatcheva, L. Beretta, J. J. Pan, M. B. Fallon, J. B. McCormick, S. P. Fisher-Hoch

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

This study aimed to estimate the prevalence and risk factors for hepatitis C virus (HCV) infection in Mexican Americans living in South Texas. We tested plasma for the presence of HCV antibody from the Cameron County Hispanic Cohort (CCHC), a randomized, population-based cohort in an economically disadvantaged Mexican American community on the United States/Mexico border with high rates of chronic disease. A weighted prevalence of HCV antibody of 2·3% [n = 1131, 95% confidence interval (CI) 1·2-3·4] was found. Participants with diabetes had low rates of HCV antibody (0·4%, 95% CI 0·0-0·9) and logistic regression revealed a statistically significant negative association between HCV and diabetes (OR 0·20, 95% CI 0·05-0·77) after adjusting for sociodemographic and clinical factors. This conflicts with reported positive associations of diabetes and HCV infection. No classic risk factors were identified, but important differences between genders emerged in analysis. This population-based study of HCV in Mexican Americans suggests that national studies do not adequately describe the epidemiology of HCV in this border community and that unique risk factors may be involved.

Original languageEnglish (US)
Pages (from-to)297-305
Number of pages9
JournalEpidemiology and infection
Volume144
Issue number2
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

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Hepacivirus
Hepatitis C Antibodies
Population
Virus Diseases
Confidence Intervals
Vulnerable Populations
Mexico
Hispanic Americans
Epidemiology
Chronic Disease
Logistic Models

Keywords

  • Hepatitis C virus
  • infectious disease epidemiology
  • Mexican American
  • prevalence of disease
  • public health

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

Cite this

Hepatitis C virus in Mexican Americans : A population-based study reveals relatively high prevalence and negative association with diabetes. / Watt, G. P.; Vatcheva, K. P.; Beretta, L.; Pan, J. J.; Fallon, M. B.; McCormick, J. B.; Fisher-Hoch, S. P.

In: Epidemiology and infection, Vol. 144, No. 2, 01.01.2016, p. 297-305.

Research output: Contribution to journalArticle

Watt, G. P. ; Vatcheva, K. P. ; Beretta, L. ; Pan, J. J. ; Fallon, M. B. ; McCormick, J. B. ; Fisher-Hoch, S. P. / Hepatitis C virus in Mexican Americans : A population-based study reveals relatively high prevalence and negative association with diabetes. In: Epidemiology and infection. 2016 ; Vol. 144, No. 2. pp. 297-305.
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