High-resolution SPECT with a CdZnTe detector array and a scintillation camera

M. C. Wu, G. A. Kastis, S. J. Balzer, D. W. Wilson, H. B. Barber, Harrison H Barrett, M. W. Dae, B. H. Hasegawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

The emerging significance of transgenic animal research has motivated the development of radionuclide imaging systems for mice and other small animals. In this work we compare the performance of a scintillation camera with a pinhole collimator (aperture diameter = 0.5 mm, magnification = 8-10) to that of a pixellated CdZnTe hybrid detector array with a parallel-hole collimator (pixel pitch = 0.380 mm, collimator aspect ratio = 27:1, collimator efficiency = 5×10-5) for SPECT. A "mouse heart" phantom (annular cavity filled with aqueous pertechnetate simulating myocardial perfusion, OD = 5.1 mm, ID = 1.6 mm) and a miniature Carlson grid phantom (3.2 mm cold squares, 4.8 mm pitch) were imaged. Both systems produced high quality images in which objects smaller than two millimeters were resolved. The pinhole system's cone-beam geometry offers advantages, such as an easily variable field of view, and disadvantages such as increased distortion and a decreased field of view close to the pinhole. The semiconductor detector and parallel-hole collimator provide excellent spatial resolution close to the collimator with a fixed field of view of 25 × 25 mm. We believe that both systems will find applications in small animal imaging.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
EditorsD. Merelli, J. Surget, M. Ulma
Volume3
StatePublished - 2000
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: Oct 15 2000Oct 20 2000

Other

Other2000 IEEE Nuclear Science Symposium Conference Record
CountryFrance
CityLyon
Period10/15/0010/20/00

Fingerprint

Scintillation
Animals
Cameras
Detectors
Semiconductor detectors
Radioisotopes
Imaging systems
Image quality
Cones
Aspect ratio
Pixels
Imaging techniques
Geometry

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Wu, M. C., Kastis, G. A., Balzer, S. J., Wilson, D. W., Barber, H. B., Barrett, H. H., ... Hasegawa, B. H. (2000). High-resolution SPECT with a CdZnTe detector array and a scintillation camera. In D. Merelli, J. Surget, & M. Ulma (Eds.), IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 3)

High-resolution SPECT with a CdZnTe detector array and a scintillation camera. / Wu, M. C.; Kastis, G. A.; Balzer, S. J.; Wilson, D. W.; Barber, H. B.; Barrett, Harrison H; Dae, M. W.; Hasegawa, B. H.

IEEE Nuclear Science Symposium and Medical Imaging Conference. ed. / D. Merelli; J. Surget; M. Ulma. Vol. 3 2000.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wu, MC, Kastis, GA, Balzer, SJ, Wilson, DW, Barber, HB, Barrett, HH, Dae, MW & Hasegawa, BH 2000, High-resolution SPECT with a CdZnTe detector array and a scintillation camera. in D Merelli, J Surget & M Ulma (eds), IEEE Nuclear Science Symposium and Medical Imaging Conference. vol. 3, 2000 IEEE Nuclear Science Symposium Conference Record, Lyon, France, 10/15/00.
Wu MC, Kastis GA, Balzer SJ, Wilson DW, Barber HB, Barrett HH et al. High-resolution SPECT with a CdZnTe detector array and a scintillation camera. In Merelli D, Surget J, Ulma M, editors, IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 3. 2000
Wu, M. C. ; Kastis, G. A. ; Balzer, S. J. ; Wilson, D. W. ; Barber, H. B. ; Barrett, Harrison H ; Dae, M. W. ; Hasegawa, B. H. / High-resolution SPECT with a CdZnTe detector array and a scintillation camera. IEEE Nuclear Science Symposium and Medical Imaging Conference. editor / D. Merelli ; J. Surget ; M. Ulma. Vol. 3 2000.
@inproceedings{90c7f5ff295e45578f4fe3c7ff1dd30a,
title = "High-resolution SPECT with a CdZnTe detector array and a scintillation camera",
abstract = "The emerging significance of transgenic animal research has motivated the development of radionuclide imaging systems for mice and other small animals. In this work we compare the performance of a scintillation camera with a pinhole collimator (aperture diameter = 0.5 mm, magnification = 8-10) to that of a pixellated CdZnTe hybrid detector array with a parallel-hole collimator (pixel pitch = 0.380 mm, collimator aspect ratio = 27:1, collimator efficiency = 5×10-5) for SPECT. A {"}mouse heart{"} phantom (annular cavity filled with aqueous pertechnetate simulating myocardial perfusion, OD = 5.1 mm, ID = 1.6 mm) and a miniature Carlson grid phantom (3.2 mm cold squares, 4.8 mm pitch) were imaged. Both systems produced high quality images in which objects smaller than two millimeters were resolved. The pinhole system's cone-beam geometry offers advantages, such as an easily variable field of view, and disadvantages such as increased distortion and a decreased field of view close to the pinhole. The semiconductor detector and parallel-hole collimator provide excellent spatial resolution close to the collimator with a fixed field of view of 25 × 25 mm. We believe that both systems will find applications in small animal imaging.",
author = "Wu, {M. C.} and Kastis, {G. A.} and Balzer, {S. J.} and Wilson, {D. W.} and Barber, {H. B.} and Barrett, {Harrison H} and Dae, {M. W.} and Hasegawa, {B. H.}",
year = "2000",
language = "English (US)",
volume = "3",
editor = "D. Merelli and J. Surget and M. Ulma",
booktitle = "IEEE Nuclear Science Symposium and Medical Imaging Conference",

}

TY - GEN

T1 - High-resolution SPECT with a CdZnTe detector array and a scintillation camera

AU - Wu, M. C.

AU - Kastis, G. A.

AU - Balzer, S. J.

AU - Wilson, D. W.

AU - Barber, H. B.

AU - Barrett, Harrison H

AU - Dae, M. W.

AU - Hasegawa, B. H.

PY - 2000

Y1 - 2000

N2 - The emerging significance of transgenic animal research has motivated the development of radionuclide imaging systems for mice and other small animals. In this work we compare the performance of a scintillation camera with a pinhole collimator (aperture diameter = 0.5 mm, magnification = 8-10) to that of a pixellated CdZnTe hybrid detector array with a parallel-hole collimator (pixel pitch = 0.380 mm, collimator aspect ratio = 27:1, collimator efficiency = 5×10-5) for SPECT. A "mouse heart" phantom (annular cavity filled with aqueous pertechnetate simulating myocardial perfusion, OD = 5.1 mm, ID = 1.6 mm) and a miniature Carlson grid phantom (3.2 mm cold squares, 4.8 mm pitch) were imaged. Both systems produced high quality images in which objects smaller than two millimeters were resolved. The pinhole system's cone-beam geometry offers advantages, such as an easily variable field of view, and disadvantages such as increased distortion and a decreased field of view close to the pinhole. The semiconductor detector and parallel-hole collimator provide excellent spatial resolution close to the collimator with a fixed field of view of 25 × 25 mm. We believe that both systems will find applications in small animal imaging.

AB - The emerging significance of transgenic animal research has motivated the development of radionuclide imaging systems for mice and other small animals. In this work we compare the performance of a scintillation camera with a pinhole collimator (aperture diameter = 0.5 mm, magnification = 8-10) to that of a pixellated CdZnTe hybrid detector array with a parallel-hole collimator (pixel pitch = 0.380 mm, collimator aspect ratio = 27:1, collimator efficiency = 5×10-5) for SPECT. A "mouse heart" phantom (annular cavity filled with aqueous pertechnetate simulating myocardial perfusion, OD = 5.1 mm, ID = 1.6 mm) and a miniature Carlson grid phantom (3.2 mm cold squares, 4.8 mm pitch) were imaged. Both systems produced high quality images in which objects smaller than two millimeters were resolved. The pinhole system's cone-beam geometry offers advantages, such as an easily variable field of view, and disadvantages such as increased distortion and a decreased field of view close to the pinhole. The semiconductor detector and parallel-hole collimator provide excellent spatial resolution close to the collimator with a fixed field of view of 25 × 25 mm. We believe that both systems will find applications in small animal imaging.

UR - http://www.scopus.com/inward/record.url?scp=0034593632&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034593632&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0034593632

VL - 3

BT - IEEE Nuclear Science Symposium and Medical Imaging Conference

A2 - Merelli, D.

A2 - Surget, J.

A2 - Ulma, M.

ER -