High speed multiple echo acquisition (HISTO): A rapid and simultaneous assessment of fat and iron content in liver by1HMRS, validation on phantoms and patients

N. Pineda-Alonso, D. Martin, Q. Xu, P. Sharma, M. Vos, X. Hu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Proton MR Spectroscopy (1H MRS) offers a means for noninvasively determining hepatic lipids (HL) and provides acceptable spectral resolution and high sensitivity even with low amounts of HL. 1H-MRS is also used to accurately quantify the iron overload in the liver. In this work, we introduce a technique that allows the rapid, accurate and simultaneous assessment of fat and iron content which could be applied for single breath hold liver MRS. The feasibility and accuracy of this technique has been demonstrated experimentally in phantoms and applied to patients with fatty liver disease.

Original languageEnglish (US)
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, Proceedings, ISBI
Pages1533-1536
Number of pages4
DOIs
StatePublished - Sep 10 2008
Externally publishedYes
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: May 14 2008May 17 2008

Publication series

Name2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period5/14/085/17/08

Keywords

  • Iron
  • Lipids
  • Liver
  • MRS
  • Steatosis
  • T2

ASJC Scopus subject areas

  • Biomedical Engineering

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    Pineda-Alonso, N., Martin, D., Xu, Q., Sharma, P., Vos, M., & Hu, X. (2008). High speed multiple echo acquisition (HISTO): A rapid and simultaneous assessment of fat and iron content in liver by1HMRS, validation on phantoms and patients. In 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI (pp. 1533-1536). [4541301] (2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI). https://doi.org/10.1109/ISBI.2008.4541301