Highlights From the American Association of Pharmaceutical Scientists/ International Transporter Consortium Joint Workshop on Drug Transporters in Absorption, Distribution, Metabolism, and Excretion

From the Bench to the Bedside – Clinical Pharmacology Considerations

Patrick T Ronaldson, B. Bauer, A. F. El-Kattan, H. Shen, L. Salphati, S. W. Louie

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The American Association of Pharmaceutical Scientists/International Transporter Consortium Joint Workshop on Drug Transporters in absorption, distribution, metabolism, and excretion was held with the objective of discussing innovative advances in transporter pharmacology. Specific topics included (i) transporters at the blood-brain barrier (BBB); (ii) emerging transport proteins; (iii) recent advances in achieving hepatoselectivity and optimizing clearance for organic anion-transporting polypeptide (OATP) substrates; (iv) utility of animal models for transporter studies; and (v) clinical correlation of transporter polymorphisms. Here, we present state-of-the-art highlights from this workshop in these key areas of focus.

Original languageEnglish (US)
Pages (from-to)419-422
Number of pages4
JournalClinical Pharmacology and Therapeutics
DOIs
StatePublished - Nov 1 2016

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Clinical Pharmacology
Education
Blood-Brain Barrier
Pharmaceutical Preparations
Anions
Carrier Proteins
Animal Models
Pharmacology
Peptides

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

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