Hippocampal complex and retrieval of recent and very remote autobiographical memories

Evidence from functional magnetic resonance imaging in neurologically intact people

T Lee Ryan, Lynn Nadel, Katrina Keil, Karen Putnam, David Schnyer, Theodore "Ted" Trouard, Morris Moscovitch

Research output: Contribution to journalArticle

215 Citations (Scopus)

Abstract

It has been argued that the role of the hippocampus in memory is time-limited: during a period of memory consolidation, other brain regions such as the neocortex are said to acquire the ability to support memory retention and retrieval on their own. An alternative view is that retention and retrieval of memory for autobiographical episodes depend on the hippocampal complex, regardless of the age of the memory. We examined the participation of the hippocampal complex in a functional magnetic resonance imaging (fMRI) study in which participants were asked to recollect autobiographical events that occurred either within the last 4 years or more than 20 years ago. We found equivalent levels of hippocampal activation in both conditions in all participants (N = 10). In addition, activation in neocortical regions did not differ as a function of the age of the memory, even though most of the recent memories recalled were less than 2 years old and the remote memories more than 35 years old. The results support the notion that the hippocampal complex participates in retention and recovery of even very old autobiographical memories, and place boundary conditions on theories of memory consolidation.

Original languageEnglish (US)
Pages (from-to)707-714
Number of pages8
JournalHippocampus
Volume11
Issue number6
DOIs
StatePublished - 2001

Fingerprint

Episodic Memory
Long-Term Memory
Magnetic Resonance Imaging
Aptitude
Neocortex
Hippocampus
Brain
Retention (Psychology)

Keywords

  • Autobiographical memory
  • Consolidation
  • Functional MRI
  • Hippocampus
  • Medial temporal lobe
  • Retrieval

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Hippocampal complex and retrieval of recent and very remote autobiographical memories : Evidence from functional magnetic resonance imaging in neurologically intact people. / Ryan, T Lee; Nadel, Lynn; Keil, Katrina; Putnam, Karen; Schnyer, David; Trouard, Theodore "Ted"; Moscovitch, Morris.

In: Hippocampus, Vol. 11, No. 6, 2001, p. 707-714.

Research output: Contribution to journalArticle

@article{31bd1837e6774686bee0cbb1ad6079a2,
title = "Hippocampal complex and retrieval of recent and very remote autobiographical memories: Evidence from functional magnetic resonance imaging in neurologically intact people",
abstract = "It has been argued that the role of the hippocampus in memory is time-limited: during a period of memory consolidation, other brain regions such as the neocortex are said to acquire the ability to support memory retention and retrieval on their own. An alternative view is that retention and retrieval of memory for autobiographical episodes depend on the hippocampal complex, regardless of the age of the memory. We examined the participation of the hippocampal complex in a functional magnetic resonance imaging (fMRI) study in which participants were asked to recollect autobiographical events that occurred either within the last 4 years or more than 20 years ago. We found equivalent levels of hippocampal activation in both conditions in all participants (N = 10). In addition, activation in neocortical regions did not differ as a function of the age of the memory, even though most of the recent memories recalled were less than 2 years old and the remote memories more than 35 years old. The results support the notion that the hippocampal complex participates in retention and recovery of even very old autobiographical memories, and place boundary conditions on theories of memory consolidation.",
keywords = "Autobiographical memory, Consolidation, Functional MRI, Hippocampus, Medial temporal lobe, Retrieval",
author = "Ryan, {T Lee} and Lynn Nadel and Katrina Keil and Karen Putnam and David Schnyer and Trouard, {Theodore {"}Ted{"}} and Morris Moscovitch",
year = "2001",
doi = "10.1002/hipo.1086",
language = "English (US)",
volume = "11",
pages = "707--714",
journal = "Hippocampus",
issn = "1050-9631",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Hippocampal complex and retrieval of recent and very remote autobiographical memories

T2 - Evidence from functional magnetic resonance imaging in neurologically intact people

AU - Ryan, T Lee

AU - Nadel, Lynn

AU - Keil, Katrina

AU - Putnam, Karen

AU - Schnyer, David

AU - Trouard, Theodore "Ted"

AU - Moscovitch, Morris

PY - 2001

Y1 - 2001

N2 - It has been argued that the role of the hippocampus in memory is time-limited: during a period of memory consolidation, other brain regions such as the neocortex are said to acquire the ability to support memory retention and retrieval on their own. An alternative view is that retention and retrieval of memory for autobiographical episodes depend on the hippocampal complex, regardless of the age of the memory. We examined the participation of the hippocampal complex in a functional magnetic resonance imaging (fMRI) study in which participants were asked to recollect autobiographical events that occurred either within the last 4 years or more than 20 years ago. We found equivalent levels of hippocampal activation in both conditions in all participants (N = 10). In addition, activation in neocortical regions did not differ as a function of the age of the memory, even though most of the recent memories recalled were less than 2 years old and the remote memories more than 35 years old. The results support the notion that the hippocampal complex participates in retention and recovery of even very old autobiographical memories, and place boundary conditions on theories of memory consolidation.

AB - It has been argued that the role of the hippocampus in memory is time-limited: during a period of memory consolidation, other brain regions such as the neocortex are said to acquire the ability to support memory retention and retrieval on their own. An alternative view is that retention and retrieval of memory for autobiographical episodes depend on the hippocampal complex, regardless of the age of the memory. We examined the participation of the hippocampal complex in a functional magnetic resonance imaging (fMRI) study in which participants were asked to recollect autobiographical events that occurred either within the last 4 years or more than 20 years ago. We found equivalent levels of hippocampal activation in both conditions in all participants (N = 10). In addition, activation in neocortical regions did not differ as a function of the age of the memory, even though most of the recent memories recalled were less than 2 years old and the remote memories more than 35 years old. The results support the notion that the hippocampal complex participates in retention and recovery of even very old autobiographical memories, and place boundary conditions on theories of memory consolidation.

KW - Autobiographical memory

KW - Consolidation

KW - Functional MRI

KW - Hippocampus

KW - Medial temporal lobe

KW - Retrieval

UR - http://www.scopus.com/inward/record.url?scp=0035686290&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035686290&partnerID=8YFLogxK

U2 - 10.1002/hipo.1086

DO - 10.1002/hipo.1086

M3 - Article

VL - 11

SP - 707

EP - 714

JO - Hippocampus

JF - Hippocampus

SN - 1050-9631

IS - 6

ER -