Histopathology of hereditary muscular dystrophy of the domestic turkey (Meleagris gallopavo)

John A Schmitz, J. A. Harper

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The histopathology of hereditary muscular dystrophy was studied in homozygous dystrophic turkeys of various ages. Lesions were severe at ten weeks of age but absent at seven weeks or less. Lesions at ten weeks consisted of variation in fiber size and contour with acute necrosis of individual muscle fibers. Myopathic characteristics were similar at 16 and 24 weeks but with fewer dystrophic fibers and slower fiber destruction. Fat deposition was mild at 24 weeks and there were disseminated foci of endomysial proliferation in dystrophic muscle at 16 and 24 weeks. Pectoral and alar muscles were dystrophic but no lesions were detected in gastrocnemius muscle myocardium, central and peripheral nervous system tissue or visceral organs. Mean diameters and nuclear numbers of muscle fibers were significantly less in pectoral muscles of dystrophic turkeys than in controls and did not increase significantly from ten to 24 weeks of age as did controls.

Original languageEnglish (US)
Pages (from-to)389-396
Number of pages8
JournalCanadian Journal of Comparative Medicine
Volume39
Issue number4
StatePublished - 1975
Externally publishedYes

Fingerprint

muscular dystrophy
Muscular Dystrophies
histopathology
Pectoralis Muscles
lesions (animal)
Muscles
muscles
muscle fibers
Nerve Tissue
Peripheral Nervous System
peripheral nervous system
Myocardium
Skeletal Muscle
Necrosis
Central Nervous System
myocardium
Fats
central nervous system
necrosis
Meleagris gallopavo

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Histopathology of hereditary muscular dystrophy of the domestic turkey (Meleagris gallopavo). / Schmitz, John A; Harper, J. A.

In: Canadian Journal of Comparative Medicine, Vol. 39, No. 4, 1975, p. 389-396.

Research output: Contribution to journalArticle

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