Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Lindsey Egan, Patricia Connolly, L. Joseph Wheat, Deanna Fuller, Thomas E. Davis, Kenneth S. Knox, Chadi A. Hage

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

Original languageEnglish (US)
Pages (from-to)93-95
Number of pages3
JournalMedical mycology
Volume46
Issue number1
DOIs
StatePublished - Feb 1 2008
Externally publishedYes

Keywords

  • Antigen detection
  • Beta-glucan
  • Histoplasmosis

ASJC Scopus subject areas

  • Infectious Diseases

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    Egan, L., Connolly, P., Wheat, L. J., Fuller, D., Davis, T. E., Knox, K. S., & Hage, C. A. (2008). Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test. Medical mycology, 46(1), 93-95. https://doi.org/10.1080/13693780701642235