Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay

L. Joseph Wheat, Emily Hackett, Michelle Durkin, Patricia Connolly, Ruta Petraitiene, Thomas J. Walsh, Kenneth S Knox, Chadi Hage

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.

Original languageEnglish (US)
Pages (from-to)638-640
Number of pages3
JournalClinical and Vaccine Immunology
Volume14
Issue number5
DOIs
StatePublished - May 2007
Externally publishedYes

Fingerprint

Histoplasmosis
Aspergillus
Immunoenzyme Techniques
Enzymes
Histoplasma
Antigens
Infection

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Wheat, L. J., Hackett, E., Durkin, M., Connolly, P., Petraitiene, R., Walsh, T. J., ... Hage, C. (2007). Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay. Clinical and Vaccine Immunology, 14(5), 638-640. https://doi.org/10.1128/CVI.00479-06

Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay. / Wheat, L. Joseph; Hackett, Emily; Durkin, Michelle; Connolly, Patricia; Petraitiene, Ruta; Walsh, Thomas J.; Knox, Kenneth S; Hage, Chadi.

In: Clinical and Vaccine Immunology, Vol. 14, No. 5, 05.2007, p. 638-640.

Research output: Contribution to journalArticle

Wheat, LJ, Hackett, E, Durkin, M, Connolly, P, Petraitiene, R, Walsh, TJ, Knox, KS & Hage, C 2007, 'Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay', Clinical and Vaccine Immunology, vol. 14, no. 5, pp. 638-640. https://doi.org/10.1128/CVI.00479-06
Wheat, L. Joseph ; Hackett, Emily ; Durkin, Michelle ; Connolly, Patricia ; Petraitiene, Ruta ; Walsh, Thomas J. ; Knox, Kenneth S ; Hage, Chadi. / Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay. In: Clinical and Vaccine Immunology. 2007 ; Vol. 14, No. 5. pp. 638-640.
@article{e922f3ffe2cc4570ae52306a97ecd43b,
title = "Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay",
abstract = "We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.",
author = "Wheat, {L. Joseph} and Emily Hackett and Michelle Durkin and Patricia Connolly and Ruta Petraitiene and Walsh, {Thomas J.} and Knox, {Kenneth S} and Chadi Hage",
year = "2007",
month = "5",
doi = "10.1128/CVI.00479-06",
language = "English (US)",
volume = "14",
pages = "638--640",
journal = "Clinical and Vaccine Immunology",
issn = "1556-6811",
publisher = "American Society for Microbiology",
number = "5",

}

TY - JOUR

T1 - Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay

AU - Wheat, L. Joseph

AU - Hackett, Emily

AU - Durkin, Michelle

AU - Connolly, Patricia

AU - Petraitiene, Ruta

AU - Walsh, Thomas J.

AU - Knox, Kenneth S

AU - Hage, Chadi

PY - 2007/5

Y1 - 2007/5

N2 - We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.

AB - We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.

UR - http://www.scopus.com/inward/record.url?scp=34250331175&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34250331175&partnerID=8YFLogxK

U2 - 10.1128/CVI.00479-06

DO - 10.1128/CVI.00479-06

M3 - Article

C2 - 17344352

AN - SCOPUS:34250331175

VL - 14

SP - 638

EP - 640

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

SN - 1556-6811

IS - 5

ER -