HLA in Egyptian children with biliary atresia

Hassan H Hassan, Moustafa El-Ayyouti, Samia Hawas, Ahmed Abdalla, Yousif Al-Tonbary, Mohammed Bassiouny, Anna Boneberg, Shadia El-Sallab

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

Original languageEnglish (US)
Pages (from-to)432-434
Number of pages3
JournalThe Journal of Pediatrics
Volume141
Issue number3
DOIs
StatePublished - Sep 2002
Externally publishedYes

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Biliary Atresia
HLA Antigens
Haplotypes
Population

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hassan, H. H., El-Ayyouti, M., Hawas, S., Abdalla, A., Al-Tonbary, Y., Bassiouny, M., ... El-Sallab, S. (2002). HLA in Egyptian children with biliary atresia. The Journal of Pediatrics, 141(3), 432-434. https://doi.org/10.1067/mpd.2002.127506

HLA in Egyptian children with biliary atresia. / Hassan, Hassan H; El-Ayyouti, Moustafa; Hawas, Samia; Abdalla, Ahmed; Al-Tonbary, Yousif; Bassiouny, Mohammed; Boneberg, Anna; El-Sallab, Shadia.

In: The Journal of Pediatrics, Vol. 141, No. 3, 09.2002, p. 432-434.

Research output: Contribution to journalArticle

Hassan, HH, El-Ayyouti, M, Hawas, S, Abdalla, A, Al-Tonbary, Y, Bassiouny, M, Boneberg, A & El-Sallab, S 2002, 'HLA in Egyptian children with biliary atresia', The Journal of Pediatrics, vol. 141, no. 3, pp. 432-434. https://doi.org/10.1067/mpd.2002.127506
Hassan HH, El-Ayyouti M, Hawas S, Abdalla A, Al-Tonbary Y, Bassiouny M et al. HLA in Egyptian children with biliary atresia. The Journal of Pediatrics. 2002 Sep;141(3):432-434. https://doi.org/10.1067/mpd.2002.127506
Hassan, Hassan H ; El-Ayyouti, Moustafa ; Hawas, Samia ; Abdalla, Ahmed ; Al-Tonbary, Yousif ; Bassiouny, Mohammed ; Boneberg, Anna ; El-Sallab, Shadia. / HLA in Egyptian children with biliary atresia. In: The Journal of Pediatrics. 2002 ; Vol. 141, No. 3. pp. 432-434.
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