HLA in Egyptian children with biliary atresia

Hassan H. A-Kader, Moustafa El-Ayyouti, Samia Hawas, Ahmed Abdalla, Yousif Al-Tonbary, Mohammed Bassiouny, Anna Boneberg, Shadia El-Sallab

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

Original languageEnglish (US)
Pages (from-to)432-434
Number of pages3
JournalJournal of Pediatrics
Volume141
Issue number3
DOIs
StatePublished - Sep 2002

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    A-Kader, H. H., El-Ayyouti, M., Hawas, S., Abdalla, A., Al-Tonbary, Y., Bassiouny, M., Boneberg, A., & El-Sallab, S. (2002). HLA in Egyptian children with biliary atresia. Journal of Pediatrics, 141(3), 432-434. https://doi.org/10.1067/mpd.2002.127506