Hypercapnic respiratory failure during weaning

neuromuscular capacity versus muscle loads.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Patients who fail a weaning trial develop hypercapnia as a result of alveolar hypoventilation, which, in turn, is caused by an imbalance between the respiratory muscle load and capacity. In some patients, especially those with obstructive lung diseases, respiratory muscle performance is impaired as a result of dynamic hyperinflation and paradoxical motion of the rib cage and abdomen. Worsening of pulmonary mechanics causes further embarrassment of the respiratory muscles and can lead to marked alterations of oxygen use by the peripheral tissues. The development of rapid shallow breathing together with worsening of pulmonary mechanics results in inefficient clearance of COcf152cf1 during a failed weaning attempt.

Original languageEnglish (US)
Pages (from-to)385-405
Number of pages21
JournalRespiratory Care Clinics of North America
Volume6
Issue number3
StatePublished - Sep 2000
Externally publishedYes

Fingerprint

Respiratory Muscles
Weaning
Respiratory Insufficiency
Mechanics
Muscles
Obstructive Lung Diseases
Hypoventilation
Lung
Hypercapnia
Abdomen
Respiration
Oxygen

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Hypercapnic respiratory failure during weaning : neuromuscular capacity versus muscle loads. / Jubran, A.; Parthasarathy, Sairam.

In: Respiratory Care Clinics of North America, Vol. 6, No. 3, 09.2000, p. 385-405.

Research output: Contribution to journalArticle

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