Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental mice

M. Khairuzzaman, A. K. Azad, Ahsan Habib, Atiqur Rahman, Jannatun Ferdous, Ariful Islam, Tauhidur Rahman, G. Tawabul Alam Chowdhury

Research output: Contribution to journalArticle

Abstract

Diabetes is emerging new threats through different complications with time. Present study was designed to evaluate a hypoglycemic activity of Polyalthia longifolia leaves ethanol extract of along with analgesic activity. Oral glucose tolerance test showed significant result at dose 500mg/kg body weight of mice but not significant at dose 250mg/kg compare to control group where metformin was used as a reference standard. Analgesic activity of Polyalthia longifolia extract by acetic acid induced writhing method also showed mentionable effects that was 58% at dose 500mg/kg and 70% at 250mg/kg compare with standard diclofenac 78% writhing inhibition.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalPharmacologyonline
Volume3
StatePublished - Dec 30 2018
Externally publishedYes

Keywords

  • Acetic acid
  • Analgesic activity
  • Glucose tolerance
  • Hypoglycemic
  • Polyalthia longifolia

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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  • Cite this

    Khairuzzaman, M., Azad, A. K., Habib, A., Rahman, A., Ferdous, J., Islam, A., Rahman, T., & Chowdhury, G. T. A. (2018). Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental mice. Pharmacologyonline, 3, 229-234.