Ia antigens on non-lymphoid tissues their origins and functions

Douglas F. Nixon, Jenny Pan Yun Ting, Jeffrey A Frelinger

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Ia molecules are encoded in the 1 region of the mouse major histocompatibility complex (MIX) and expressed as surface antigens on certain immunologically active cells (reviewed in Ref. 1). B cells, subsets of T helper and T suppressor cells and accessory, antigen-presenting cells are Ia-positive (Ia+) while T killer cells and natural killer cells are not. This article discusses the nature and function of Ia+ cells found in non-lymphoid tissues, some of which are immunologically involved while others are not obviously so.

Original languageEnglish (US)
Pages (from-to)339-342
Number of pages4
JournalImmunology Today
Volume3
Issue number12
DOIs
StatePublished - 1982
Externally publishedYes

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Histocompatibility Antigens Class II
B-Lymphocyte Subsets
Antigen-Presenting Cells
Surface Antigens
Helper-Inducer T-Lymphocytes
Major Histocompatibility Complex
Natural Killer Cells

ASJC Scopus subject areas

  • Immunology

Cite this

Ia antigens on non-lymphoid tissues their origins and functions. / Nixon, Douglas F.; Ting, Jenny Pan Yun; Frelinger, Jeffrey A.

In: Immunology Today, Vol. 3, No. 12, 1982, p. 339-342.

Research output: Contribution to journalArticle

Nixon, Douglas F. ; Ting, Jenny Pan Yun ; Frelinger, Jeffrey A. / Ia antigens on non-lymphoid tissues their origins and functions. In: Immunology Today. 1982 ; Vol. 3, No. 12. pp. 339-342.
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