Identification and quantification of alpha-methylfentanyl in post mortem specimens

A Jay Gandolfi, A. J. Gandolfi, Thomas P Davis, R. A. Morano

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectometry. Despropionylmethylfentanyl was also detected in the extracts of the victim's tissues.

Original languageEnglish (US)
Pages (from-to)139-142
Number of pages4
JournalJournal of Analytical Toxicology
Volume6
Issue number3
StatePublished - 1982

Fingerprint

Drug Overdose
Tissue
Tissue Extracts
Narcotics
Bile
Liver
drug
Blood
Nitrogen
Gases
blood
Detectors
nitrogen
gas
Pharmaceutical Preparations
alpha-methylfentanyl
tissue
neodymium pyrocatechin disulfonate
detector

ASJC Scopus subject areas

  • Analytical Chemistry
  • Health, Toxicology and Mutagenesis
  • Toxicology

Cite this

Identification and quantification of alpha-methylfentanyl in post mortem specimens. / Gandolfi, A Jay; Gandolfi, A. J.; Davis, Thomas P; Morano, R. A.

In: Journal of Analytical Toxicology, Vol. 6, No. 3, 1982, p. 139-142.

Research output: Contribution to journalArticle

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AB - Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectometry. Despropionylmethylfentanyl was also detected in the extracts of the victim's tissues.

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