Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

Henk J. Swarts, Frank J.M. Verhagen, Jim A. Field, Joannes B.P.A. Wijnberg

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1- (3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (2) and 1-(3'-chloro-4'- methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp, BOS55 was also a new finding.

Original languageEnglish (US)
Pages (from-to)1110-1114
Number of pages5
JournalJournal Of Natural Products
Volume61
Issue number9
DOIs
StatePublished - Sep 1 1998
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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