Identification of a highly divergent HIV type 2 and proposal for a change in HIV type 2 classification

Florence Damond, Michael Worobey, Pauline Campa, Isabelle Farfara, Gilles Colin, Sophie Matheron, Françoise Brun-Vézinet, David L. Robertson, François Simon

Research output: Contribution to journalArticle

113 Scopus citations

Abstract

We report the complete genome sequence of a highly divergent strain of human immunodeficiency virus type 2 (HIV-2), 96FR12034, identified in France from a patient of West African origin. This lineage, H, represents only the third definitive instance of a monkey-to-human transfer of SIVsm that has given rise to pathogenic HIV-2. As the different "subtypes" of HIV-2 are analogous to the different groups of HIV-1 we propose that HIV-2 subtypes henceforth by renamed groups in agreement with the HIV Nomenclature Committee. The single-strain lineages C to G and the 96FR12034 lineage identified here should be considered only as putative groups until related strains are identified that confirm circulation of these viruses in the human population.

Original languageEnglish (US)
Pages (from-to)666-672
Number of pages7
JournalAIDS Research and Human Retroviruses
Volume20
Issue number6
DOIs
StatePublished - Jun 1 2004

    Fingerprint

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

Cite this

Damond, F., Worobey, M., Campa, P., Farfara, I., Colin, G., Matheron, S., Brun-Vézinet, F., Robertson, D. L., & Simon, F. (2004). Identification of a highly divergent HIV type 2 and proposal for a change in HIV type 2 classification. AIDS Research and Human Retroviruses, 20(6), 666-672. https://doi.org/10.1089/0889222041217392