Image reconstruction of optical tomographic data from a highly scattering medium

J. Lee, D. W. Wilson, Harrison H Barrett, Arthur F Gmitro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently new technologies for detecting biomolecules have been developed and are opening a new era of medical imaging. Chemiluminescence and fluorescence are emerging as promising tools for these tasks. These molecules emit optical photons that can be observed outside the body. Unfortunately, they are heavily scattered and absorbed in biological tissue. This is an obstacle for determining a way of mapping an original source distribution. In order to overcome this obstacle, we suggest a new concept, Optical Emission Computed Tomography(OpECT) and test its feasibility with computer simulation.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsL.E. Antonuk, M.J. Yaffe
Pages792-799
Number of pages8
Volume4320
DOIs
Publication statusPublished - 2001
EventMedical Imaging 2001: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2001Feb 20 2001

Other

OtherMedical Imaging 2001: Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/18/012/20/01

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Keywords

  • Chemiluminescene
  • Fluorescence
  • ML-EM algorithm
  • Monte-Carlo Simulation
  • OpECT
  • Scattering Medium

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Lee, J., Wilson, D. W., Barrett, H. H., & Gmitro, A. F. (2001). Image reconstruction of optical tomographic data from a highly scattering medium. In L. E. Antonuk, & M. J. Yaffe (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4320, pp. 792-799) https://doi.org/10.1117/12.430909