Imaging current flow in lobster nerve cord using the acoustoelectric effect

Russell Witte, Ragnar Olafsson, Sheng Wen Huang, Matthew O'Donnell

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Ultrasound traversing a biologic fluid or tissue generates a local change in electrical conductivity known as the acoustoelectric effect. The authors exploit this interaction to image ionic current injected into the abdominal segment of the lobster nerve cord. A pair of recording electrodes detected the acoustoelectric signal induced by pulses of focused ultrasound (1.4 or 7.5 MHz). The signal was linear with injected current at 2 MPa (0.7 μV/mA cm 2) and pressure at 75 mA/cm2 (23 μV/MPa). Acoustoelectric imaging of biocurrents potentially enhances spatial resolution of traditional electrophysiology and merits further study as an imaging modality for neural applications.

Original languageEnglish (US)
Article number163902
JournalApplied Physics Letters
Volume90
Issue number16
DOIs
StatePublished - Apr 30 2007
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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