Immunoglobulins on the surface of human appendix lymphocytes

A. V. Jubert, C. M. Mc Bride, G. Mavligit, J. U. Gutterman, Evan M Hersh

Research output: Contribution to journalArticle

Abstract

The proportion of lymphocytes in the appendix and peripheral blood with IgM, IgG, IgA, and IgE cell surface determinants was measured by membrane immunofluorescence. IgM was found on 9.2% of appendix lymphocytes, compared to 3.5% of simultaneously collected peripheral blood lymphocytes (p=0.01). In contrast, IgG was found on 6.3% of peripheral blood lymphocytes compared to only 3.0% of appendix lymphocytes (p=0.2). The difference between IgM and IgG on the appendix lympocytes, however, was highly significant (p<0.001). There was no difference in the number of cells with IgA or IgE determinants between the 2 populations. These results indicated that a good proportion of the human appendix lymphocytes are B cells. The higher level of IgM, if substantiated by further studies, would point to some central role for the human appendix lymphocyte immunologic reactivity.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalImmunological Communications
Volume3
Issue number1
StatePublished - 1974
Externally publishedYes

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B-Cell Antigen Receptors
Lymphocytes
Immunoglobulin M
Immunoglobulin G
Immunoglobulin A
Immunoglobulin E
Fluorescent Antibody Technique
B-Lymphocytes
Cell Count
Membranes
Population

ASJC Scopus subject areas

  • Immunology

Cite this

Jubert, A. V., Mc Bride, C. M., Mavligit, G., Gutterman, J. U., & Hersh, E. M. (1974). Immunoglobulins on the surface of human appendix lymphocytes. Immunological Communications, 3(1), 1-9.

Immunoglobulins on the surface of human appendix lymphocytes. / Jubert, A. V.; Mc Bride, C. M.; Mavligit, G.; Gutterman, J. U.; Hersh, Evan M.

In: Immunological Communications, Vol. 3, No. 1, 1974, p. 1-9.

Research output: Contribution to journalArticle

Jubert, AV, Mc Bride, CM, Mavligit, G, Gutterman, JU & Hersh, EM 1974, 'Immunoglobulins on the surface of human appendix lymphocytes', Immunological Communications, vol. 3, no. 1, pp. 1-9.
Jubert AV, Mc Bride CM, Mavligit G, Gutterman JU, Hersh EM. Immunoglobulins on the surface of human appendix lymphocytes. Immunological Communications. 1974;3(1):1-9.
Jubert, A. V. ; Mc Bride, C. M. ; Mavligit, G. ; Gutterman, J. U. ; Hersh, Evan M. / Immunoglobulins on the surface of human appendix lymphocytes. In: Immunological Communications. 1974 ; Vol. 3, No. 1. pp. 1-9.
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